產(chǎn)品屬性：
產(chǎn)品名稱 | Pentoxifylline-d6 |
規(guī)格 | 1mg、5mg |
貨號 | EY-01Y14993 |
Cas No.: 1185879-03-1
別名: N/A
化學名: N/A
分子式: C13H12D6N4O3
分子量: 284.3
溶解度: Acetonitrile: soluble,DMSO: soluble,Methanol: soluble
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Pentoxifylline-d6 is intended for use as an internal standard for the quantification of pentoxifylline by GC- or LC-MS. Pentoxifylline is a hemorrheologic agent.1 It increases the deformability of washed isolated human erythrocytes when used at a concentration of 100 μM.2 Pentoxifylline (1, 2, and 3 mM) inhibits ADP-induced platelet aggregation in isolated human whole blood.3 It inhibits thrombus formation induced by ADP in a hamster cheek pouch model when administered at doses of 5, 10, and 20 mg/kg.4 Formulations containing pentoxifylline have been used in the treatment of intermittent claudication.1.Ward, A., and Clissold, S.P.Pentoxifylline. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic efficacyDrugs34(1)50-97(1987)
2.S?oczyńska, K., Kózka, M., P?kala, E., et al.In vitro effect of pentoxifylline and lisofylline on deformability and aggregation of red blood cells from healthy subjects and patients with chronic venous diseaseActa Biochim. Pol.60(1)129-135(2013)
3.Magnusson, B., Gunnarsson, M., Berntorp, E., et al.Effects of pentoxifylline and its metabolites on platelet aggregation in whole blood from healthy humansEur. J. Pharmacol.581(3)290-295(2008)
4.Michal, M., Giessinger, N., and Schr?er, R.Reduced thrombus formation in vivo after administration of pentoxifylline (Trental)Thromb. Res.56(3)359-368(1989)
特別提醒公司產(chǎn)品僅供科研使用
