產(chǎn)品屬性：
產(chǎn)品名稱(chēng) | S-5751 |
規(guī)格 | 500μg、1mg、5mg |
貨號(hào) | EY-01Y17509 |
Cas No.: 209268-36-0
別名: N/A
化學(xué)名: N/A
分子式: C25H31NO4S
分子量: 441.6
溶解度: DMSO: 36 mg/ml
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
S-5751 is an antagonist of the prostaglandin D2 (PGD2) receptor DP1 (Ki = 1.6 nM) that shows at least 20-fold selectivity over receptors for thromboxane and prostacyclin, as well as the PGE2 receptor EP2. Orally administered S-5751 blocks PGD2-induced plasma exudation in the conjunctiva (ED50 = 0.099 mg/kg) and suppresses antigen-induced allergic responses in guinea pigs. S-5751 has been used to distinguish signaling of PGD2 through its two receptors, DP1 and DP2 (also known as CRTH2).
特別提醒公司產(chǎn)品僅供科研使用
